A few niggles, let's say...
1: All of those cooling-slots on the top of the A500/600/1200 (same goes for the C64!) seem to be designed to attract and hold dust and be almost impossible to clean (without a scrubbing brush and water!)
2: The constant clicking/active floppy drives!
3: No proper VGA/SVGA non-interlaced, 24 bit modes in AGA
4: Location of the mouse ports - all over the place on the big-box Amigas...
5: The impossibly tight-fit of the A1200 expansion slot - maybe the expansion card makers are also to blame a bit? Why not make the cards (or slot) easier to fit stuff into?
6: The A4000 case - as ugly as a bag of spanners
7: Did I mention the ugly A4000 case?
:-)
Mike.