Without wishing to paint a huge 'flame-target' on my back, I'd have to say that XP Pro has been the best OS I've ever used - certainly the most stable. People seem to put the boot into anything that's M$. And don't forget - it runs WinUAE! :-)
I also run Ubuntu 7.10/8.04/8.10, which are nice, but on the same hardware I've always found XP mroe stable and faster, plus it has far more apps (well, the ones I need anyway!) available for it than anything else.
I've also tried OSX, but just can't get used to it.
Other than that I have to say that AmiKit 1.5 is the most impressive "OS" I use - if you haven't tried it and you have a Windows box, I strongly suggest on giving it a go. It certainly is the best thing this side of OS4.1/Morphos 2.0!
Cheers,
Mike.