I once put together a CD with boot floppy to run a Video Toaster for emergency use. I did a fresh install to the hard drive and burned all the files onto a cd. I then made a boot floppy to mount the CD and assign all the resources to the CD. Since the Workbench files were also on the cd I only need a few files on the floppy to get it to work.
In addition I believe there was compression programs for executables to reduce the file size. Very useful for floppys. There is also a program I remember called reorg. This was useful to keep the floppy from doing alot of seeking and helped reduce boot times.