there should only be two jumper settings for the desktop A4000 memory.
pins 1-2 is for simms of 1 or 2Mb and pins 2-3 is for simms of 4 or 8Mb.
4-8Mb ram with 4x 1Mb or 4x 2Mb simms
16Mb ram with 4x 4Mb or 2x 8mb simms.
with the 8Mb simms, leave one simm slot between each simm (pretend it takes up two slots as this is what it does in the addressing)
there should be a 2Mb simm in the chipram slot. this is NOT upgradable to 8Mb. the A4000 doesn't contain the logic to handle more than 2Mb chip ram. (and its not just a case of soldering a line between some chips to make it work.) some of the latest desktop A4000's came with the chip ram soldered directly onto the mainboard - so the only simm slots you had are for fast ram. (4 simm slots as opposed to 5)
as for the hard disk, the seagate 250Mb drive is about as usefull as an ugly paperweight. get a modern drive. it'll be able 5 times faster (2.5Mb/s a sec as opposed to 500K/s). 20Gb drives can be had for 35 UKP these days.
and yes, you can have more than one drive on the IDE bus.
i have a little device that i used to use to double the number of IDE devices (2 to 4). had two hard drives, IDE CD, and IDE ZIP drives. slow. but worked.