On another note if I put in a larger than 4GB HDD and partition it as 4GB would there be any issues?
Nope. There's a chance it will be recognised by HDtools as something entirely different, but just correct those figures until they represent the correct values.
For example: I have had an 20 GB drive I used for testing showing up as 60 MB. After partitioning (which took a while to figure out), it worked without problems.
