I've tried using a cleaning disk (not one with the alcohol fluid, but a dry one that doesn't spin) but that did not work.
Strange thing is: both diskdrives do the same, shouldn't I look somewhere else for the drive error?
About the Agnus, I'll look later today what it says.
@Mike: what trapdoor expansion was in the A500+ originally? I've played on one about 19 years ago, a friend of mine had one, but I've never opened his A500+ 
A500+ originally had 1MB of chip memory on the motherboard with an optional 1MB chip in the trapdoor (A500+ boards came without the battery-backed clock since A500+ already had a clock on the motherboard). When Commodore stock dried up on the original A500's they started selling a lot of A500 systems with A500+ motherboards, minus some of the extra chips. Full A500+ would have had ECS Agnus & Denise, 2.04 ROM, and the 1MB on the board. From the photo you posted it looks like you'd just need to solder on the extra chips to bring yours up to capacity; you can probably find those on a dead A500+ board (lots out there, killed by battery leakage) or remove from any A501-style memory expansion board.
Re: the floppy drive, try swapping out Paula and the CIA's, perhaps?