At work I have a revision 4.2 A2000 (German made MB) that the agency has been using since 1987. A few years ago we got a GVP-M 2060 combo board.
That board takes both the GVP 64 pin simms & -standard- 72 pin simms. I have 128MB of ram, a 68060 @ 50MHZ and a four gig (Qunatum, I think) hard drive connected to it. Everything works fine.
The machine also has a Video Toaster 4000, a Hydra ethernet card and a Catweasel V2 card. My only problem is that one of my multi-sync monitors died & I can't get a Toaster compatible scan-doubler.
(BTW, if you do go scrounging thru old Mac's you might get a surprise. One or two models used 64 pin simms. Sorry they are not compatible with GVP cards. However I did upgrade my GVP 030 board from 25 to 40MHZ with Mac parts.)