Also remember if you have a common first part of your email adress such as yourfirstname@myisp.xx there are viruses that use name-lists (of common firstnames and alike) and will sniff upp all domains found on an infected machine and send mails to all names in it's name-list + all domains found on the infected machine.
I know... got boomber with up to 500 virus mails a day on my brian@myisp.xx when MyDoom first started it's terror due to this "feature" (calculating around 100K a mail I had to empty my inbox several times a day over a 2 week period due to this or no legit mail would've had a chanse to reach me, damn my ISP for not offering antivirus on incomming mails!).