TBH, I've always wanted a game like Baldur's Gate II for the Amiga. An accelerated Amiga should be able to handle something like that gloriously.
I'm willing to help cough up the 3D animations converted to sprites for such a game. Currently, I'm doing graphics for a open sourced Bard's Tale Construction Set called BTBuilder. It's just Linux and Windows only and it's in alpha, but quite far.