Yes, you can run it through an emulator, but then you have to use the D-pad to move the cursor, which is a pain. ScummVM can run the SCUMM data files if you extract them from the ROM, but the extractor utility uses one of several built-in indices for the game resources, corresponding to the different-language releases of the NES version. It doesn't support the prototype, and Quietust apparently refuses to add support. The source is available, and if I knew enough about SCUMM I could just construct an additional index, but I don't.