It'll speed up a lot software using it
i think its corresponding to the possibility of using little endian on some legacy amiga rtg solutions. for instance mediator/voodoo has both, however parallel usage of both kind of modes at the same time was not recommended as leading to crashes.
i dont remember well, but there was some speed difference when running pc ports depending on what endian rtg mode you made available to it. possibly it was little endian, where real time endian conversion wasnt neccessary.