@IanP
I would also think there are only an handful of masochists still using an Amiga for 3D graphics work.
I think that would be quite a fun use of a Vampire card. Some people still enjoy messing around with Lightwave on the X1000/5000 machines so why not on the Classics? Plus FPU is useful for TFX, DrawStudio 2 and now Beats of Rage!