I do own the Amithlon/XL suite but I must admit I often use WinUAE more than I use Amithlon. Primarily because I own a GeForce4 TI/4200 and most video modes are unsupported. Not to mention the fact that my ethernet card is not supported and fails to function correctly.
All in all the latest version of WinUAE is much more easily configured. I will look at Amithlon2 when it is released.
I use my amiga emulation software to do development on the Amiga and since my A3000 doesn't have enough RAM (and RAM is hard to come by for total ammounts greater than 16MB).