It depends on what you're doing. If, for example, you wish to run mp3s, it should run through AHI. If you're using OctaMED, you'll have to run the Puh de Baer switch, in the Amithlon Dir, to make it emulate the Paula. It's flawless on my 1.4mhz machine.
I haven't had ANY problems with my Amithlon box, except with the CD player. I have AC97 on my mobo, but I couldn't trigger the CDPlayer. I had to install my SB128 and then use the AC97Mixer (which didn't like my version of the CODEC) to unmute the channel, then pull the SB card out.
Now, too bad the floppies don't work. =^\