Some people enjoy the extra sense of achievement of doing something professional on Amiga. Years ago there was guy who wrote his own plotter driver and used an AmigaONE to print vinyl banners as part of his business.
Amiga (any platform) is not suited for professional work, missing components like 64bit, memory protection or multicore support are the least problem, more problematic is missing drivers for 3rd party hardware like printers and expecially no up-to-date software. I would never even guess to use amigas for professional work, it is a nice hobby I waste some time on when I have some time left, not more not less.