My interest in the A1222 is kind of morbid -- I think it might be the last Amiga, and I don't want to miss out on that, having been there at the beginning. It sort of bookends everything.
Even so, I'm hoping for a successful jump to another architecture and a continuance of Amiga. I am aware of the enormous legal and technical obstacles that make this unlikely, but ... never give up! 
At this point, the last introduction would appear to be the P5040 variant of the X5000, IF that gets produced.
But I too am gearing up toward the idea of one final PPC system (in this case either a P5020 or P5040 based X5000), running under MorphOS primarily, although I will install OS4.1.
These systems should last us awhile, as older Eyetech AmigaOnes and bPlan Pegasos 1 & 2 models are still in use.
Video drivers and other support should improve in the future, and hopefully we can concentrate on application software for awhile.
Aeon has stated it has plans for the future, the MorphOS team has announced an eventual shift to X64 that will take quite awhile, so for now we've reached a high point in our development similar to that which occurred when the original AmigaOne and Pegasos systems were released.
We have multi-core systems that could allow for future development, modern expansion slots to support newer video cards and accessories, and while we could use better USB support for USB 3.0, that's not too shabby.
