Portability will be possible and desired, but initially x86/Mac/iPhone using a cool free development kit called Unity3D. It would be great if something like that existed for Amiga (a game engine with usability comparable to a good authoring software).
Unfortunately porting Unity3D to the next-gen Amigas would require a source-code license for Unity which would probably cost more than the professional license at $1499 USD not to mention it would need better graphics drivers than any non-next-gen system has.