At 320x200, you're limited by the CPU, graphics card vs AGA and Zorro bus have very little influence. In fact, my A2000 and A4000, both with 060/50 and Picasso IV performed _identical_ in the timedemo benchmarks. At 66MHz the 4000 was 1 FPS quicker IIRC.
You might notice a few FPS difference at higher resolutions, but they are generally unplayable anyway. 640x480 is somewhat doable if the screensize is set very small.