The only problems Ive ever had with amiga hardware were self induced (ie. punching holes through them out of frustration with games (the Lion King game cost me quite a bit of money, which is silly for many reasons, not the least of which being that it's not even a great game)). Apart from my own stupdity though Ive never had any major problems, and that's including an a1200+bppc+grex+voodoo3 system, which most people tend to say are problematic (although personally Ive yet to see reasons for this reputation). Granted it's dead now, but that's due to dodgey electricity at my house and rapid power fluctuations (pretty costly night that, wasnt only my bppc+grex that died).
Personally I get more frustrated with the "NG" amiga options.