Can't do it for my main working computer, as I depend on and require Final Cut Pro and Aperture as well as parts of the Adobe Creative Suite.
But my Sam440 has pretty well replaced my Amiga 4000D as my main fun computer. Fun for me is messing about with creative applications, not games, I might add. I have abandoned Microsoft Entourage on my "main" machine for e-mail in favor of YAM on my Sam, however.