@esc Are you use GREX settings in winuae maybe? If so, as it was noted startup-sequence were changed and overwritten. But your original one backed up to the same plz (something like startup-sequence-upd2). So if you had in your old startup-sequence something about grex or whatever else, you may need to copy that to the new startup-sequence. For one user it was "C: BootLoader COMMANDLINE = "Grex NoRamPager NoDiskPager", so recheck to be sure.