Interesting. I am not convinced that a SCSI interface is the best idea, though, even with a SCSI->SATA adapter, the price of a hard drive goes up a bit. My suggestion would be a small IDE interface, or better a 2.5" SATA interface. A clean-up of the chips might give enough room to actually rest the hard drive on the board to slide into the SATA port, like some of the USB enclosures. A CF interface would be cool, too, but perhaps feature-creep.
A USB interface would be nice to have, something like a built-in Deneb. A lot of work to make this board Zorro III, would it be?
hrmmmm Very cool, indeed. Looking forward to updates.