@DonnyEMU
Of course it would run, OS X is based heavily on Unix. The thing about hardware is this... hardware will run on *any* OS as long as drivers for that OS are coded. Also OS X has alot of drivers for hardware built in.
Linux/Unix is very stable on x86/x86-64 systems, thus OS X should be just as stable as well. However you gotta remember something, Apple Computer is a systems company, not an OS only company, so of course they are going to intentionally make their main OS' kernel 100% compatible for a specific chipset that's in their systems.
As for "oddball" hardware... that's a very smart thing for Apple to not generally support them; that's called great Quality Control, and ensures a tight smooth running computer.