On high end there's 3 good ones. HDRec, ProStationAudio and AudioEvolution. They don't have the wide variety of state of the art plugins available on other architectures but provide decent non linear audio editing. Besides, you can use external hardware for processing and just do the NLE on them. Can't remember if any supported 24bit though, maybe AudioEvolution does.
Don't know about Octamed to be honest never tried it. But then again I just play guitar and record a few riffs here and there (wich hopefully will turn into songs some day;))