Carefully look at Errata number 1 (I've got no idea if the SMD hub chip crasbe is going to glue onto the board his this "problem", but if it has, then no mice or keyboards will be working)
I would guess that wouldn't pass initial tests, so he wouldn't use that chipset. Something to be aware of tho....
and number 6 (not that the other ones aren't bad, but the last one would make me refrain from using any MSD devices with it!).
It sounds like that's just something to be aware of for the USB stack (don't use "auto-increment"). I don't see how this affects me at all..
The performance of USB (especially over clockport) is probably going to be throttled by many other things before this would cause an issue..
And remember, this is supposed to be low cost, so slower isn't a big deal. People who need more speed can buy the more expensive faster cards. ;-)
So, I don't see any major issues holding this back..
Looking forward to a possible clockport version.
desiv