Octamed SS, as a generally system friendly app already runs just fine on OS4 on the BlizzPPC. I also ran it fine on my A1XE (before it died), by using "The Marstrix" AHI redirection tool for faking a Maestro sound card which is one of the built in output options for mix mode.
Worth noting that on a graphics card, it works best on it's own 8-bit screen rather than just running it on a copy of the workbench screen mode.