For me some of the best were:
Hired Guns!!!!
Pirates!
Syndicate
Settlers
Lord of the Realms *surprised no one else mentioned this*
Zeewolf 1 & 2
Another world
Alien Breed series
Jaguar XJ220
Supercars 2
Midnight resistance
The Dizzy games
Quality coin-op conversions also made the machine in my mind. Compared to what everyone else had (spectrum, C64) seeing Chase HQ and Turbo Outrun look so close to the arcade counterparts was what told me thhe machine was special...and I was only about 10.