Aside of DOOM, and Mednafen (not on any Amiga OS for some VERY STRANGE reason), I have to say that ScummVM takes up more of my gaming time than anything else!
I have tested it with nearly everything it is said to support, and 95% of the games work just as they should!
One aspect about ScummVM that really gets me excited is the fact that now I can play the talkie version of games that Amiga only had a Talkie Less versions of. Space Quest IV, Dream Web, Space Quest I remake, and on and on and on.
Another bonus of ScummVM games is that you can kick back, relax and play them all via mouse.
Ya man, ScummVm RULES!!!!
As for the classic Amiga variant, I have not touched those very much, so I'm not as familiar with them as I am with ScummVM on MorphOS, Aros, Haiku, Dreamcast, Classic XBOX, and the Wii.