Hello,
I still own Quake, even though i have no Amiga to play it on. But it was fairly playable on my A1200 with 060 and AGA, i got between 10-20fps. It was okay, but a 060 AGA is the bare minimum i reckon. It flies pretty well on PPC, i got 30-40fps on my 160. The minimum hardware requirements for Quake are: 020+FPU, AGA and 8meg RAM. So this game will not run on OCS/ECS. That is why a complex setup on A2000 and A500 seems more likely.